NO EVIDENCE FOR SELECTION OF HIV-1 WITH ENHANCED GAG-PROTEASE OR NEF FUNCTION AMONG BREAKTHROUGH INFECTIONS IN THE CAPRISA 004 TENOFOVIR MICROBICIDE TRIAL.

No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial.

Use of antiretroviral-based microbicides for HIV-1 prophylaxis could Sterilization Packaging introduce a transmission barrier that inadvertently facilitates the selection of fitter viral variants among incident infections.To investigate this, we assessed the in vitro function of gag-protease and nef sequences from participants who acquired HIV-1 du

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Fluorescence spectroscopy: A sensitive tool for identifying land-use and climatic region effects on the characteristics of water-extractable soil organic matter

Water-extractable organic matter (WEOM) is an indicator of active and labile pools of soil organic matter (SOM).Land-use is expected to have a major effect on SOM, yet the effects of different land-uses on WEOM are not well understood.Reported trends in the changes in water-extractable organic C (WEOC) concentrations following changes in land-use a

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Dual-energy CT: A new frontier in oncology imaging

Malignant tumors have risen to prominence as the leading threat to both life and the overall health of individuals.Precision medicine relies heavily on precise imaging.Among the plethora of imaging techniques, the advantages of dual-energy computed tomography (CT) in tumor diagnosis and treatment are becoming increasingly pronounced.Accurate Steril

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Adult ADHD: Risk Factor for Dementia or Phenotypic Mimic?

Attention-deficit hyperactivity disorder (ADHD) has historically been considered a disorder of childhood and adolescence.However, it is now recognized that ADHD symptoms persist into adulthood in up to 60% of individuals.Some of the cognitive symptoms that characterize ADHD (inability to provide sustained attention or mental effort, difficulty orga

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